ABSTRACT
Disabilities in upper limb due to stroke are the major problems in hemiplegic patients. Recently, joystick method as new method is applied for the improvment of upper limb disabilities. This study was carried out to compare the effect of joystick in combination verses routine rehabilitation and routine rehabilitation program on hand muscles stiffness in hemiplegic patients. In this clinical trial study, 12 hemiplegic patients were randomly divided into two control and interventional groups. Subjects in the control group were received rehabilitation program with placebo joystick. Patients in interventional group were received joystick treatment with routine rehabilitation program for 10 sessions, 3 times a week. Pre and post-treatment evaluation was performed based on Wrist Robo Hab method. Flexion and pronation muscle stiffness in control patients showed non significant improvement, but in the interventional group, significant improvement were observed [P<0.05]. At the end of study, there was not any significant difference between control and interventional group. According to this finding, there was not any significant difference between the combination of joystick and rehabilitation treatment and routine rehabilitation program on the hand muscle function in hemiplegic patients
ABSTRACT
Irreversible electroporation is a new treatment modality for skin tumors ablation. In order to successful treatment, all of tumoral tissues must be exposed to intense electric field. In addition, the heat that produced during the surgery has adverse effect on recovery procedure. This study was done to evaluate the thermal distribution in ablation of squamous cell carcinoma skin tumors using irreversible electroporation. In this study numerical modeling by finite element was used for determination of electrical and thermal distribution in healthy and tumoral tissues. Three-Dimensional Model was done using MR imaging of patient with squamous cell carcinoma in FEMLAB v3.5a software. Electric field distribution determined using Laplace equation and distribution of thermal damage calculated using bioheat equation and Arrhenius equation. This calculation was done for different geometry parameters of needle and plate electrodes. Thermal damage of first-degree burn was not observed in any cases. However in high voltage, volume with temperature above 43[degree sign]C reach to 10% of tumoral tissue and 3% of healthy tissue. The study show that the voltage applied to the electrodes and the distance between the electrodes can have the greatest impact on the thermal and electrical distributions. Although needle electrode showed better electric coverage in tumoral area. This study showed that it can be possible to select optimized electric and geometric parameter to select electrode for complete tumor ablation, control of thermal damage in tumoral and healthy tissues
Subject(s)
Humans , Electrochemotherapy , Carcinoma, Squamous Cell , Skin Neoplasms , Ablation TechniquesABSTRACT
Disability of upper extrimity from stroke are often permanent. Despite numerous functional problems, there is less attention to upper exterimity disabilitis than lower limbs. Some new methods of treatment focuses on using the magnetic stimulation as a means brain currents to produce therapeutic effects. This study was done to evalute the effect of low frequency repeatitive transcranial magnetic stimulation to improve motor function and grip force of upper limb in hemiplegic patients. This clinical trial study was done on 12 stroke hemiplegic patients in Firoozgar hospital in Tehran, Iran during 2009-10. Patients in group I, recieved rehabilitation program with placebo magnetic stimulation, and patients in group II, received magnetic stimulation with routine rehabilitation program for 10 session, 3 times in week. Pre and post were evaluated by Barthel and Fugl-Meyer indeces and dynamometer. Data were analyzed using SPSS-15, Kolmogorov-Smirnov, paired t-test, independent t-test and Wilcoxon signed tests. According to Barthel and Fugl-Meyer indeces both groups I, II showed significant improvement [P<0.05]. Using dynamometer, it was demenstrated that grip force of upper limb in group I was not significant but this index in group II was significant after intervention [P<0.05]. This study showed that low frequency repeatitive truscrianial magnetic stimulation has therapuetic effect on grip force of upper limb
ABSTRACT
Disabilities of upper extremities, as a sequela of stroke, often result in permanent functional complications which have received less attention in comparison to lower limb disabilities. Magnetic stimulation is a new therapeutic method which is used for induction of currents in the brain. The aim of this study was to compare the effect of magnetic stimulation on the wrist and elbow joints movements and grip force with that of routine rehabilitation. 12 hemiplegic patients were assigned to two groups. Patients in group I, received routine rehabilitation with placebo magnetic stimulation, and patients in group II, received magnetic stimulation with routine rehabilitation for 10 session, 3 times a week. Pre and post treatment evaluations were performed by use of Barthel index, Fugl-Meyer Motor Impairment Scale and dynamometer. In group I, Barthel and Fugl-Meyer indexes showed significant improvement, but no significant improvement noted in the rate of grip force. Group II, showed significant improvement in Barthel and Fugl-Meyer indexes and rate of grip force. When conventional treatment is not effective, rTMS can improve force and function of hand muscles in chronic hemiplegic patients
ABSTRACT
This study was planned to examine the effects of whole-body exposure to GSM-950 MHz electromagnetic fields [EMFs] on acquisition and consolidation of spatial memory in rats using a water maze task. In experiment 1, the animals were given two blocks of five trials per day for three consecutive days in a water maze task. The interval between blocks was 4h. Before each training session, the animals were exposed to 950 MHz EMFs for 45 min with lower-[0.835 mW/cm[2]] or higher-power [1.166 mW/cm[2]] densities. In experiment 2, the animals were given two blocks of 5 trials with a 3 min interval between blocks. Immediately after the last trial, they were exposed to EMFs for 45 min with lower-or higher-power densities. In both experiments, 48 h after the last training day a 60 s probe test was done. Results from experiment1 [pre-training exposure to EMFs] indicated no significant differences in performances of exposed and non-exposed groups either during acquisition [learning] or during probe test [memory retention]. Results from experiment 2 [post training exposure to EMFs] also indicated no significant differences among groups during acquisition or probe test. In these experiments, no effect of exposure to 950 MHz on acquisition or consolidation of spatial navigation of rats in a water maze was detected